The MGH Biostatistics Center supports MGH Investigators undertaking basic research projects. Drawing on a team of highly-skilled biostatisticians, the Biostatistics Center offers consultations and expertise on a range of relevant areas to researchers as they launch new translational and basic research projects including Grant submission/resubmission; Design for non-grant projects and feasibility consultations; Education on a statistical topic; Analysis planning and advice; Assistance with response to a manuscript/journal review.
Consulting for basic science projects is sponsored by ECOR, and can be accessed by contacting Dr. Dianne Finkelstein, Director of Biostatistics
Center for Integration of Medicine & Innovative Technology (CIMIT)
The mission of CIMIT is to improve patient care by facilitating the collaboration of scientists, engineers, and clinicians to catalyze development of innovative technology, emphasizing minimally invasive diagnosis and therapy. CIMIT is bringing together clinicians at the forefront of medicine, scientists and engineers working at the frontiers of high technology, and industry to focus on solutions to perplexing health care problems.
Clinical Research Center
The goal of the MGH Clinical Research Center is to provide a clinical laboratory and other support for medical scientists who conduct human subject research. Investigations include studies of normal and abnormal human physiology and studies of the cause, prevention, control and cure of diseases that afflict individuals of all ages, races and ethnic backgrounds.
Clinical Trials @ Partners
Clinical Trials @ Partners is a service to help you take part in research going on at Partners HealthCare. Whether you are looking for research in a certain health area or want to learn more about studies you might qualify for, Clinical Trials @ Partners can help you easily and quickly find the right study for you. You can also use this site to help research teams design their studies and to learn more about how research is done.
Division of Clinical Research
The mission of the Division of Clinical Research at Massachusetts General Hospital is to support researchers in their efforts to increase the quantity, quality and efficiency of translating basic science advances into improved care for our patients.
The Division of Clinical Research promotes clinical research by:
» Supporting clinical and translational research at Mass General
through specific centers and units
» Nurturing the next generation of Mass General clinical investigators
» Increasing Mass General's overall clinical research funding
» Expanding Mass General's pool of clinical research mentors
» Providing hands-on support to overcome the logistical challenges
faced by clinical investigators
Free services provided to investigators:
» Consultations with CRP faculty (6-8 hours)
» IND/IDE submissions and project management
» Assistance with subject recruitment
» Identification of potential funding sources
» Budgeting for clinical studies
» Help with National Institutes of Health (NIH) and Patient Centered
Outcomes Research (PCORI) applications
Tools and Resources for Clinical Researchers
Executive Committee on Research (ECOR)
ECOR is the central body in MGH research governance and reports to the MGH President and to the General Executive Committee (GEC). ECOR has responsibility for providing strategic guidance to MGH leadership and MGH Trustees regarding future research growth and priorities within MGH, across Partners, and with affiliated external institutions. It also is responsible for providing faculty guidance on development and management of policies on human subjects, proposal review, animal care, animal studies, communications, graduate education, and research facilities (including research space). Various initiatives and relevant subcommittees are established to carry out these responsibilities.
Its membership includes two elected representatives elected from each of the three HMS faculty ranks (Assistant Professor, Associate Professor, and Professor), as well as representatives elected from the Chiefs’ Council and appointed faculty members and senior management, including the MGH President and the MGPO President. The committee meets the second and fourth Monday of the month.
The current Chair is Robert Kingston, PhD, (Chief of Molecular Biology); the Vice Chair is David N. Louis, MD (Chief of Pathology); and the Past Chair is Daniel Haber, MD, PhD (Director of the MGH Cancer Center). Each position is a three year term; the vice chair usually succeeds to the roles of Chair and Past Chair, thereby assuring continuity over a 9-year time period. These three people, the Sr. Vice President for Research, the Chiefs of Surgery and Medicine, and the Director of the Clinical Research Program, along with the Director of ECOR, form the ECOR Executive Committee.
Research Council and MGH Faculty Meetings
The Research Council, sponsored by ECOR, meets monthly as a town meeting of the MGH investigator community and is open to the entire research community. The ECOR elected representatives serve as the Executive Committee and the Research Council chair and co-chair are the two full-professor elected representatives to ECOR. The goal of these meetings is to provide communication between ECOR and the investigator community and to bring important issues and resources to the attention of the research community.
Recently, the elected representatives have instituted Faculty meetings to offer an opportunity for faculty to discuss shared concerns. The plan is to hold these meetings three times per year (in lieu of Research Council in any given month).
ECOR representatives are able to speak to your interests and concerns in discussions and planning for research at MGH. Representatives are expected to: attend ECOR meetings, attend Research Council meetings, serve on the ECOR Council and meet formally with members of the research community as needed. There are a total of six elected members, two from each faculty rank (Professor, Associate Professor and Assistant Professor). Elected representatives serve a 3-year term. To ensure a balance of continuity and renewal, their terms are staggered so that two seats are up for election every year.
The current Elected Faculty Representatives are:
» Sylvie Breton, PhD, Professor (elected while Associate Professor)
» Henry M. Kronenberg, MD, Professor
» Alice Shaw, MD, PhD, Assistant Professor
» Susan A. Slaugenhaupt, PhD, Associate Professor
» Lynda Stuart, MBBS, PhD, Assistant Professor
» Rudolph E. Tanzi, PhD, Professor
Harvard Catalyst / The Harvard Clinical and Translational Science Center
Harvard Catalyst | The Harvard Clinical and Translational Science Center is dedicated to improving human health by enabling collaboration and providing tools, training and technologies to clinical and translational investigators. As a shared enterprise of Harvard University, Harvard Catalyst resources are made freely available to all Harvard faculty and trainees, regardless of institutional affiliation or academic degree.
Harvard Catalyst works with Harvard schools and the academic healthcare centers (hospitals) to build and grow an environment where discoveries are rapidly and efficiently translated to improve human health. We catalyze research across all clinical and translational domains by providing investigators with opportunities such as pilot funding, with free resources such as biostatistics consultations, with educational programs such as the Clinical and Translational (C/T) Research Academy and over a dozen courses, and with a range of web tools that assist in data collection and team collaboration efforts.
Harvard Catalyst offers clinical and translational investigators what they need to conduct clinical experiments, including Research Resources - HC litt Image clinical research nursing, research dietician support, experimental design assistance, sample processing, data management, and information about core facilities.
Harvard Catalyst Advanced Curriculum Compendium
The Harvard Catalyst Advanced Curriculum Compendium (ACC) has been developmed to provide clinical investigators with opportunities for continuing education in clinical investigation beyond the introductory level.
Through a searchable online catalog, the Catalyst ACC offers educational opportunities to learn new methods or update existing clinical investigative skills. The compendium consists of lectures, seminars, and courses that target core competencies fundamental to successful clinical investigation.
Massachusetts General Physicians Organization (MGPO)
The MGPO is a multi-specialty medical group dedicated to excellence and innovation in patient care, teaching and research. To enhance physician efforts, the MGPO is committed to developing and maintaining an excellent management infrastructure including medical management, managed care contracting, billing and finance, customer service, human resources, information systems and marketing. The physicians of the MGPO are committed to providing medical leadership to the MGH and to working in partnership with the management and staff of the MGH toward the mutual success of both organizations.
Partners Core Facilities
The shared interdepartmental facilities at Partners bring state-of-the-art instrumentation, methodologies and expertise crucial to the promotion of research at Partners. The Partners cores not only provide high quality, cutting edge research services by in-house experts but also constitute a major educational resource for growing research enterprise.
The development of shared resources is part of the Partners cores commitment to interdisciplinary research and will be an important part of future endeavors. Cores make it possible to share wealth of expertise, facilities and equipment with the research community, allow for more efficient use of resources, promote collaboration among investigators and further enhance the competitiveness of Partners investigators to secure research funding.
Partners Human Research Committee
The Partners Human Research Committee (PHRC) is the Institutional Review Board (IRB) of Partners Research Management. The PHRC must approve all human-subject research conducted by a Partners-affiliated investigator. Human-subject research is a systematic investigation designed to develop or contribute to generalizable knowledge where an investigator obtains data on individuals either through direct intervention/interaction or through the use of identifiable private information (medical records) or specimens.
Partners Human Research Quality Improvement Program
In June 1999, the Human Research Quality Improvement Program (QI Program) was established as part of Partners Human Research Affairs, which oversees human studies conducted at Massachusetts General Hospital (MGH) and Brigham & Women's Hospital (BWH). The goal of this program is to help fulfill the institution's responsibility for ensuring compliance with Federal and State regulations governing human research, and to promote an environment in which human subject research will be conducted according to the highest standards. In doing so, the QI Program has developed and implemented various quality assurance and improvement initiatives to serve the Partners clinical research community.
(formerly known as Research Ventures and Licensing (RVL)
Partners Innovation is a division of Partners HealthCare that coordinates industrial relationships and IP management across Partners HealthCare, Brigham and Women’s Hospital, Massachusetts General Hospital and McLean Hospital.
RVL Educational Resources
Partners Innovation is a cohesive, coordinated group servicing medical inventors, thought-leaders, entrepreneurs and industry. Our goal is to take medical inventions and innovations discovered by Partners HealthCare researchers and provide the appropriate support and infrastructure to allow technology development, commercialization and, ultimately, the development of products to benefit patients.
The team has backgrounds in technology licensing, patenting, bench research, finance, funding, business, law and start-ups.
Primary functions in converting invention to innovation:
» Manage inventions arising from research
» Protect intellectual property
» Determine commercialization pathway
» Find industry partners and licensees
» Identify technology funding options
» Create marketing plans
» Support PHS academic-industry alliances
» Articles and Book Chapters: published articles from RVL and entity staff
» On-line Learning Modules: on-line learning modules provided to support your discovery of how the commercialization process works. Modules include:
• Do you have an idea? The invention process
• Technology Commercialization
• Clinical Trials and FDA Regulation
Partners Research Computing
Research Computing provides infrastructure, administrative, and translational research support and services to investigators and researchers in the Partners system. The department is organized into five groups: scientific services and infrastructure, genomics IT, specimen banking, RPDR, and research administrative systems. Infrastructure services include:
» Support and data backup for non-Partners desktops and laptops
» Help purchasing hardware and software
» Assistance in solving computing technology problems
» Secure File Transfer Service
Partners Research Management
The Partners Research Management internet was designed with the research community in mind, currently focusing on the administration of grants and contracts and features news and information about the Partners Research Management department. The website covers answers to the following questions:
» Preparing or submitting a proposal?
» Managing an award?
» Collaborating through subcontracts or contracts?
» Accounting for a grant or contract?
MGH Research Intranet
MGH has the largest hospital-based research program in the United States. The MGH Research Intranet brings together many resources that can help investigators, including:
» Grant funding information
» Pre- and post-award forms and resources
» Research policies and procedures
» Links to many external resources
PhD Steering Committee
The PhD Steering Committee is a small group of self-identified MGH-based faculty who share a common interest in enhancing the research environment on our campus with a particular focus on issues unique to people with basic science training working within a clinical department structure. We welcome hearing your comments, concerns and suggestions. For more information about this group, please contact Wilma M. Wasco, PhD or Samuel D. Rabkin, PhD.
Research Space Management Group
The mission of the RSMG at MGH is to improve the use of research space, fair space allocations, and to support the research community. RSMG is responsible for working with ECOR, Research Management and other MGH leaders to develop and implement space allocation strategies that support overall institutional research objectives. RSMG is responsible for completing annual surveys of research space utilization and for reviewing the results with Department/Center chiefs or Program Directors to anticipate changing space needs and to develop plans for meeting future research space requirements for both new and existing programs.
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